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Ozempic and other weight loss jabs linked to TEN deaths in the UK as health officials issue urgent warning

OZEMPIC and other weight loss jabs have now been linked to ten deaths in the UK.

There have also been 7,228 reports of illness associated with the drugs, citing nausea, vomiting and diarrhoea, according to the medicines watchdog.

a person is holding a ozempic pen in their hand
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Ozempic and other other weight loss jabs have been linked with ten deaths and 7,228 reported illnesses[/caption]
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Health secretary Wes Streeting has described the drugs as ‘game changing’ but warned against using them for ‘cosmetic’ purposes[/caption]

And 68 patients were admitted to hospital over their symptoms, the Medicines and Healthcare products Regulatory Agency (MHRA) said.

The reports particularly feature Wegovy and Ozempic, a “miracle” weight loss jab originally designed for managing type 2 diabetes.

They come just a few months after a doctor warned of potential fatalities as a result of the drugs, also known as glucagon-like peptide-1 receptor agonists (GLP-1RAs), after that a young girl was rushed to hospital with life-threatening symptoms.

The reports do not prove that the weight loss jabs are solely responsible for every individual case.

But they do highlight that whoever submitted them to the agency, whether patients or healthcare professionals, had a suspicion that GLP-1RAs may have been a factor.

Speaking to trade magazine Chemist and Druggist, the MHRA reiterated that some of these reports may just be unfortunate coincidences.

However, it did admit that the drugs had unpleasant and widespread side effects associated with it.

Last week, it instructed doctors to “inform patients about the common and serious side effects associated with GLP-1RAs” and “report cases of misuse”.

The up-to-date numbers follow last week’s estimate of 46 hospitalisations connected with the drugs, as of August 16.

The agency also estimated a 48 per cent increase in reports over the past two months.

Following the findings, it reiterated that drugs like Ozempic and Wegovy should not be used for “unauthorised indications such as aesthetic weight loss”.

It also warned of a potential black market for the drugs, advising patients to make sure they are prescribed by a registered professional.

This followed health secretary Wes Streeting‘s earlier warning that GLP-1RAs are not “cosmetic” treatments – and should only be used in exceptional circumstances.

Mr Streeting, who has also defended the “game changing” potential of the drugs, added: “Weight-loss drugs have enormous potential.

“When taken alongside healthy diet and exercise, they can be game changers in tackling obesity and getting people back to good health.

“But these are not cosmetic drugs that should be taken to help get a body beautiful picture for Instagram.

“These are serious medicines and should only be used responsibly and under medical supervision.

“They’re not a quick fix to lose a few pounds and buying them online without appropriate assessment can put people’s health at risk.

“Drugs approved for weight management should only be used by those tackling obesity, where diet and exercise has been tried first, and where patients are eligible.”

Last month, Mr Streeting defended plans to roll out weight loss jabs among unemployed people to kickstart a major back-to-work drive.

EVERYTHING YOU NEED TO KNOW ABOUT WEIGHT LOSS JABS

What are they?

Weight loss jabs are a hot media topic at the moment, with hundreds of success stories sharing how they helped them shed the pounds.

In March, the NHS announced it would make Wegovy, a drug made by Danish firm Novo Nordisk, available on prescription to thousands of obese Brits.

It contains the drug semaglutide, which is said to have helped reality star Kim Kardashian and Twitter boss Elon Musk lose weight.

Wegovy, which helped a third of people reduce their weight by 20 per cent in trials, will also be available from pharmacies like Boots.

Meanwhile, pharma company Eli Lilly last month announced results for its own weight loss drug tirzepatide.

The weekly injection helped overweight people drop more than two stone in 18 months.

How do they work?

The jabs work by suppressing your appetite, making you eat less calories and therefore lose weight.

To do this, an ingredient found in the fat-busting drug, known as Semaglutide, mimics the role of a natural hormone, called GLP-1.

GLP-1 is part of the signalling pathway that tells your body you have eaten, and prepares it to use the energy that comes from your food.

London GP and founder of wellgoodwellbeing.com, Dr Zoe Watson, said: “Your body naturally produces an appetite regulating hormone called glucagon-like peptide-1.

“These jabs work by regulating your appetite, which can lead to eating fewer calories and losing weight.”

Aren’t they diabetes drugs?

Both Wegovy and tirzepatide stem from drugs originally designed to treat diabetes.

Semaglutide, the active drug in Wegovy, was originally sold under the name Ozempic specifically for diabetes patients.

But they started noticing it helped suppress their appetites, stopping them eating as much and helping them shed the pounds.

So Novo Nordisk developed Wegovy, which contains the same chemical but at higher doses specifically to aid weight loss.

Wegovy is not prescribed for diabetes patients.

Tirzepatide is sold under the name Mounjaro for diabetes.

Can I get them?

Wegovy is offered on prescription to obese adults given specialist weight loss treatment.

The NHS currently also offers a similar drug called Saxenda, or liraglutide.

Both are only available on Tier 3 and Tier 4 weight management services, which means you have to be referred to weight management clinics led by experts.

GPs can’t prescribe them on their own either, Dr Watson said. 

The jabs have to be taken as part of an overall programme to help with lifestyle changes and psychological support to get the best effect from the medication prescribed. 

But despite being approved for use, the supply of Wegovy on the NHS has been postponed indefinitely because of a surge in worldwide demand.

Supply was also halved in the US because of the skyrocketing demand.

Eli Lilly said it will apply for a UK licence for tirzepatide soon, which could make it available to the NHS.

Are there any risks?

Like all medicines, the jabs do not come without side effects.

Around half of pe

ople taking the drug experience gut issues, including sickness, bloating, acid reflux, constipation and diarrhoea.

Dr Sarah Jarvis, GP and clinical consultant at patient.info, said: “One of the more uncommon side effects is severe acute pancreatitis, which is extremely painful and happens to one in 500 people.”

Other uncommon side effects include altered taste, kidney problems, allergic reactions, thyroid tumours, gallbladder problems and hypoglycemia.

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Ozempic has originally created to manage type 2 diabetes[/caption]

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From scabies and syphilis to rickets – the grim Victorian diseases making a comeback

THEY are often thought to be consigned to the history books – but experts have warned a whole host of Victorian diseases are making a comeback.

Declining vaccination rates, the cost-of-living crisispoor diets and malnutrition have all fed into the resurgence of the nasty bugs.

a collage of pictures shows a baby a woman a lung and a man with a toothpick in his mouth
Grim Victorian diseases are making a surprise comeback across UK

NHS Digital data reveals that ‘Victorian diseases’ caused almost 50,000 hospitalisations between 2018-23.

And figures from this year are unlikely to be any different, according to experts.

Here, Sun Health looks at the Victorian disease – and those that date further back – rearing their ugly heads, and share all the signs you need to watch out for.

1. SCURVY

Scurvy, first reported in Ancient Greek and Egyptian times is making a comeback, doctors have warned.

It’s a condition caused by a lack of vitamin C found in fresh fruit and veg.

The condition is typically associated with sailors enduring long voyages during the Middle Ages.

But doctors in the journal BMJ Case Reports have suggested it’s now re-emerging.

Doctors say it’s “eminently” treatable, but because it’s a disease associated with the past, it could be mistaken for other conditions.

For example, it can be confused with inflamed blood vessels (vasculitis), putting people at risk of fatal bleeding if left untreated.

Signs can appear as early as a month after a daily intake of less than 10mg of vitamin C.

Dr Helen Wall, senior GP partner from the NHS Oaks Family Practice in Bolton, tells Sun Health: “Scurvy is caused by not having enough vitamin C in your diet over a long period of time.

“One of the key things that is unique to scurvy is developing red or blue spots on the skin, usually the legs and feet.”

According to the NHS, scurvy symptoms can include:

  • Feeling very tired and weak all the time
  • Feeling irritable and sad all the time
  • Joint, muscle or leg pain
  • Swollen, bleeding gums (sometimes teeth can fall out)
  • Developing red or blue spots on the skin, usually on the legs and feet, although this may be less noticeable on brown or black skin
  • Skin that bruises easily

2. RICKETS

Rickets was widespread in the Victorian slums of Great Britain
Rickets was widespread in the Victorian slums of Great Britain

Rickets, once synonymous with poverty and poor diets, was diagnosed in 28,379 Brits from 2019 to 2023, according to an FOI to 78 hospital trusts by the Liberal Democrats.

East Kent Hospitals University NHS Trust, reported 580 cases in 2023, a 380 per cent increase on the 122 cases in 2019.

Rickets affects bone development in children, causing pain, stunted growth and soft, weak bones that can lead to deformities.

It is mostly caused by a lack of vitamin D, which is created by the body in response to sunlight but is also in foods such as fish (salmon, mackerel), red meat and egg yolks. 

The life-saving vaccines you need at every age

EIGHT WEEKS

  • 6-in-1 vaccine
  • Rotavirus vaccine
  • MenB vaccine

12 WEEKS

  • 6-in-1 vaccine (2nd dose)
  • Pneumococcal vaccine
  • Rotavirus vaccine (2nd dose)

16 WEEKS

  • 6-in-1 vaccine (3rd dose)
  • MenB vaccine (2nd dose)

ONE YEAR

  • Hib/MenC vaccine (1st dose)
  • MMR vaccine (1st dose)
  • Pneumococcal vaccine (2nd dose)
  • MenB vaccine (3rd dose)

TWO TO 15 YEARS

  • Children’s flu vaccine (every year until children finish Year 11 of secondary school)

THREE YEARS AND FOUR MONTHS

  • MMR vaccine (2nd dose)
  • 4-in-1 pre-school booster vaccine

12 TO 13 YEARS

  • HPV vaccine

14 YEARS

  • 3-in-1 teenage booster vaccine
  • MenACWY vaccine

65 YEARS

  • Flu vaccine (given every year after turning 65)
  • Pneumococcal vaccine
  • Shingles vaccine (if you turned 65 on or after 1 September 2023)

70 to 79 YEARS

  • Shingles vaccine

Source: The NHS

Signs and symptoms of rickets can include:

  • Delayed growth
  • Delayed motor skills
  • Pain in the spine, pelvis and legs
  • Muscle weakness

Because rickets softens the areas of growing tissue at the ends of a child’s bones (growth plates), it can cause skeletal deformities such as:

  • Bowed legs or knock knees
  • Thickened wrists and ankles
  • Breastbone projection

3. SCABIES

Meanwhile, the Royal College of General Practitioners has warned people not to ignore an itchy rash, which could be caused by the contagious skin condition scabies.

There are three cases in every 100,000 people living in England, according to the group, which is double the five-year seasonal average. 

The condition is caused by a mite that burrows into the skin to lay eggs.

A pharmacist can recommend a treatment but if the rash persists, see your GP.

Scabies are particularly difficult to get rid of and spread easily between people living together.

Deep cleaning of bedding, furniture and carpets is required.

The symptoms of scabies are:

  • Intense itching, especially at night
  • A raised rash or spots

4. TB

Tuberculosis is a bacterial bug that killed at least one in seven people in England at the beginning of the 19th century.

But a recent report released by the World Health Organisation warned that millions are still dying of the disease.

About 8.2 million people across the globe were diagnosed with TB in 2023.

According to the WHO, this is the highest number recorded since it began global TB monitoring in 1995.

New figures from the UKHSA in February showed an 11 per cent rise in TB cases in England in 2023, with 4,850 cases diagnosed.

Today, less than six per cent of those with TB die from the disease.

But it’s still a serious disease of the lungs that leaves people feeling exhausted, unwell and with a lack of appetite leading to weight loss.

Treatment is at least six months of antibiotics.

Symptoms of TB disease include:

  • A chronic cough
  • Fever
  • Chills
  • Loss of appetite
  • Weight loss
  • Fatigue
  • Haemoptysis (coughing up blood from the lungs and bronchial tubes)

5. 100-DAY-COUGH

Timeline reveals the symptoms of the '100-day cough' week-by-week

Whooping cough used to affect tens of thousands of people before a vaccine was given routinely in the 1950s.

But the uptake of jabs, now offered to pregnant women to protect their unborn babies, has fallen in recent years.

More than 12,000 cases of whooping cough were confirmed in England in the first seven months of the year compared to 856 in the whole of 2023, and nine babies died.

The condition is nicknamed the ‘100-day cough’ because it can last so long.

The first symptoms are similar to a cold before severe coughing bouts kick in.

After about a week, you or your child:

  • Will get coughing bouts that last for a few minutes and are worse at night
  • May make a “whoop” sound – a gasp for breath between coughs (young babies and some adults may not “whoop”)
  • May have difficulty breathing after a coughing bout and may turn blue or grey (young infants)
  • May bring up a thick mucus, which can make you vomit
  • May become very red in the face (more common in adults)

The cough may last for several weeks or months.

6. SCARLET FEVER

Another disease rife in the Victorian era was scarlet fever – and parents should still be wary today.

Anyone can catch the bug, but it most commonly affects children under the age of 10.

There was an unusual surge of cases in 2022/2023, along with Strep A and iGAS – all of which are caused by the same bacteria. 

There were almost 60,000 cases of scarlet fever and 516 deaths from iGAS, of which 61 were children, across the UK, more than double what is considered normal.

The signs typically include:

  1. High temperature
  2. Sore throat
  3. Swollen neck glands
  4. Rash 12-48 hours after initial symptoms. This usually starts on the tummy and then spreads
  5. White coating on the tongue
  6. Red cheeks

7. MEASLES

Measles symptoms can take several days to appear and sufferers may experience consequences even after recovering from the illness (Source: CDC)

There have been 2,601 cases of measles in England in 2024 so far, up 38 on this time last year.

While many of the other Victorian diseases have in fact always been present in the UK, measles was largely contained for years thanks to the MMR vaccine, which was introduced in 1988, despite millions of deaths worldwide every year.

But lower uptake in recent years means the deadly virus, mostly affecting children, has returned to levels above ‘elimination status’.

At the start of the school year, the UKHSA issued an urgent call to parents to ensure their children catch up on missed vaccinations after a surge in measles was seen in October 2023. 

The first signs of measles include:

  • A high temperature
  • A runny or blocked nose
  • Sneezing
  • A cough
  • Red, sore, watery eyes

7. SYPHILIS

Syphilis is one of the oldest known sexually transmitted infections.

Once thought to be in decline, it is now resurging at an alarming rate.

In 2022, the UK saw syphilis cases reach their highest level since 1948.

And it is not something just happening in the UK. 

There were 7.1million new cases of syphilis globally in 2020 according to WHO data.

Previously, men who have sex with men have historically been most affected by syphilis.

But infections in heterosexual men and women have more than doubled since 2019, with congenital syphilis also on the rise.

Congenital syphilis is syphilis that occurs when a mother passes the infection to her baby during pregnancy or at birth.

This form of the disease can have devastating consequences including miscarriage, stillbirth, premature births, low birth weights and the death of a baby shortly after birth.

Symptoms of syphilis include:

  • Small sores (ulcers) on your penis, vagina, or around your bottom (anus) – these are usually painless and you may only have one of them
  • Sores in other areas, including in your mouth or on your lips, hands or bottom
  • White or grey warty growths most commonly on your penis, vagina or around your anus
  • A rash on the palms of your hands and soles of your feet that can sometimes spread all over your body – this is not usually itchy
  • White patches in your mouth
  • Flu-like symptoms, such as a high temperature, headaches and tiredness
  • Swollen glands
  • Patchy hair loss on the head, beard and eyebrows

It can take three weeks or more for the symptoms of syphilis to appear after you’re infected.

Sometimes the symptoms can improve or go away completely, but if you have not been treated the infection is still in your body.

This means you can still pass it on and you’re at risk of getting serious problems later on.

Potential complications include:

  • Heart problems like angina, aortic aneurysm and heart failure
  • Brain problems like fits (seizures), memory problems, personality changes and dementia
  • Nerve problems like shooting pains, pins and needles, joint pain and gradual damage the joints
  • Problems with the skin, bones, testicles, liver and any other organ

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Affordable European Christmas market where it’s still t-shirt weather in December

EVERY Christmas an island in Europe is transformed into a festive paradise – but you won’t need your thick coat to explore it.

While most Brit holidaymakers head to Malta during the summer months, it’s also a good wintertime destination.

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Malta is still warm in December – so you can go in your t-shirt to the markets[/caption]
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The island has highs of 17C in December[/caption]

The weather in Malta in December reaches highs of 17C during the day, which is firm t-shirt and short weather for Brits.

And throughout December, Malta is home to several Christmas markets, transforming the Mediterranean island into a yuletide paradise.

One of the Christmas markets, Villa Rundle, runs from the end of November until just before Christmas Eve, making it the island’s longest-running Christmas Market.

Located in the Villa Rundle Gardens, the Christmas market is home to wooden stalls selling handmade gifts like soaps, candles, toys and sweets.

Meanwhile, Malta Artisan Christmas Market at Palazzo Pariso lasts for just one day.

This year, the market, which will be situated in Victory Square, will be decorated in twinkling fairy lights with live performances by musicians also taking place.

Given its name, you can expect local artists and creatives who will be selling handcrafted gifts and treats.

There’s also Fairyland in Valletta, running from December 10 until January 7, 2025.

Located right outside the City Gate, mulled wine and mince pies are sold at market stalls, with live performances also taking place on stage.

Another Christmas market is Christmas at Fort St Elmo in Valletta.

Running for two days in December, Heritage Malta organises family-themed events inside the Christmas village.

This year, there will be an interactive children’s area where kids can meet the big man himself and post a wish list to Father Christmas.

There are plenty of other draws to Malta too.

Valletta, the capital, has stunning Baroque architecture, museums, and the majestic St. John’s Co-Cathedral.

The country has a stunning coastline too, with a popular beach being Golden Bay.

While it might be the perfect temperature for Brit holidaymakers to wear their summer wardrobe, locals will be wrapped up in their winter gear.

Temperatures will also drop to 11C at night, so be sure to pack a jacket too.

Direct flights operate from UK cities like Manchester, London, Birmingham, Liverpool and Edinburgh.

Return fares start from as little as £37 in December.

What's it like to visit Malta?

THE Sun’s Mia Lyndon recently visited Malta – here’s what she thought.

I’M gazing up at a swirling, gold-leaf ceiling that took one man five years to paint.

Surrounding me are oil paintings, marble sculptures and an altar so bejewelled that I almost reach for my sunglasses.

No, I’m not at the Vatican or Versailles – I’m in Malta, in Valletta’s 450-year-old St John’s Co-Cathedral, which took artists more than a century to decorate.

This fortress-like building is set in the beating heart of Valletta, a UNESCO World Heritage Site and one of the world’s smallest capital cities.

After my spiritual experience, there’s time to dip into nearby Stephen Cordina Aroma & Therapy shop to buy a heavenly lavender and bergamot room diffuser, £14 (Stephencordina.com), before climbing the cobbled streets to Upper Barrakka.

This quaint, leafy park is nestled between limestone fortress walls and is the perfect spot to snap pictures of the glistening Grand Harbour.

At Upper Barrakka Kiosk, I sample traditional pastizzi – flaky, clam-shaped pastries stuffed with peas, 85p each, washed down with a can of Maltese Kinnie, £1.70, a zesty, Negroni-like soft drink, before I find family-run Trattoria da Pippo and my friends, who’ve been saving the table!

We tuck into large, sizzling pans of delicious Fillet Tartuffe, a creamy mushroom pasta, and Marina, a tagliatelli loaded with prawns and calamari, £17 per person for two sharing dishes

Here are other Christmas markets to visit in Europe.

And these are the European Christmas markets Brit holidaymakers can reach by taking a ferry from the UK.

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You might need a jumper for the evenings – but its still one of the warmer markets[/caption]

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